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Intracortical modulation, and not spinal inhibition, mediates placebo analgesia

by M. Martini, M. C. H. Lee, E. Valentini, G. D. Iannetti Abstract Suppression of spinal responses to noxious stimulation has been detected using spinal fMRI during placebo analgesia, which is therefore increasingly considered a phenomenon caused by descending inhibition of spinal activity. However, spinal fMRI is technically challenging and prone to false-positive results. Here […]

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